ACTIVE MOLECULES

• Citrus reticulata peel extract
• Oleanolic acid
• Serenoa serrulata fruit extract

INCI name

Citrus Reticulata (tangerine) Peel Extract, Oleanolic Acid, Serenoa Serrulata Fruit Extract, Magnolol/Honokiol, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Aqua/Water

DESCRIPTION

Thanks to its specific composition including Nobiletin (Tangerine peel extract), Oleanolic Acid, and Saw Palmetto Extract all encapsulated into elastic niosomal vesicles, NIO-SEBACTIVE restores natural sebum production acting at multiple levels:

• Reduce Triacylglycerol levels, the major sebum lipid component, through the inhibition of diacylglycerol acyltransferase (DGAT)
• Reduce Sebum Production Rate by 5α–Reductase inhibition
• Reduce Inflammation Signals lowering lipoxigenase and cicloxigenase levels

ORIGIN

• Biotechnological
• Plant Source

APPLICATIONS

• Sebum regulatory cream
• Sebum balancing cream
• Anti-acne cream

MECHANISM OF ACTION

NIO-SEBACTIVE controls excessive skin sebum production to reduce oily skin appearance

MAIN CHARACTERISTICS

• Inhibition of lipogenesis and sebaceous cells proliferation
• Inhibition of inflammatory signals (PGE2 and Leukotriene B)
• Inhibition of 5α-reductase enzymes, key step in sebum production

EFFICACY TEST

In Vitro

• DHT synthesis Inhibition (comparation with Finasteride)
• Sebaceous cell growth

In Vivo

• Sebum production
• Shiny complexion
• Porphyrin number
• Large pores number

CERTIFICATIONS

CONFORMITY

Halal, EcoCert, Natrue

COMPLIANCE